Search results for "lung transplant recipient"

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Clinical risk factors for invasive aspergillosis in lung transplant recipients: Results of an international cohort study

2018

BACKGROUND: Invasive aspergillosis (IA) is a frequent complication in lung transplant recipients (LTRs). Clinical risk factors for IA have not been fully characterized, especially in the era of extensive anti-fungal prophylaxis. The primary objective of this study was to evaluate the clinical risk factors associated with IA in LTRs. The secondary objective was to assess the mortality in LTRs who had at least 1 episode of IA compared with LTRs who never had experienced IA.METHODS: We conducted an international, multicenter, retrospective cohort study of 900 consecutive adults who received lung transplants between 2005 and 2008 with 4years of follow-up. Risk factors associated with IA were id…

Male0301 basic medicineAntifungal Agentsviruses030230 surgeryAspergillosisanti-fungal prophylaxis; Aspergillus spp; invasive aspergillosis; lung transplant recipient; single-lung transplant; Surgery; Pulmonary and Respiratory Medicine; Cardiology and Cardiovascular Medicine; TransplantationCohort StudiesPostoperative Complications0302 clinical medicineRisk Factorshemic and lymphatic diseasesMedicineInvasive Pulmonary AspergillosisFirst episodeMortality rateHazard ratioMiddle Agedembryonic structuresFemaleCardiology and Cardiovascular MedicineLung TransplantationCohort studyAdultPulmonary and Respiratory Medicinemedicine.medical_specialtyanimal structuresAdolescent030106 microbiologyYoung Adult03 medical and health sciencesanti-fungal prophylaxisInternal medicineHumansIntensive care medicineAgedProportional Hazards ModelsRetrospective Studiesinvasive aspergillosisTransplantationbusiness.industryProportional hazards modelAspergillus fumigatusAspergillus spp anti-fungal prophylaxis invasive aspergillosis lung transplant recipient single-lung transplantAspergillus sppRetrospective cohort studybiochemical phenomena metabolism and nutritionmedicine.diseaseSurvival Analysissingle-lung transplantTransplantationSurgerybusinesslung transplant recipientFollow-Up StudiesThe Journal of Heart and Lung Transplantation
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A challenging case of chorioretinitis and skin lesions in a lung transplant recipient

2018

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infection and infectious agentsmedicine.medical_specialtyinfectious diseaseclinical research/practicecomplication: infectioulung transplantation/pulmonologyBiopsymedicineImmunology and AllergybiopsyPharmacology (medical)Lung transplant recipientTransplantationmedicine.diagnostic_testinfection and infectious agentbusiness.industryChorioretinitisantibiotic: antifungalmedicine.diseaseinfection and infectious agents - fungalDermatologycomplication: infectiousAntibiotics antifungalInfectious disease (medical specialty)Skin lesionbusinessantibiotic: antifungal; biopsy; clinical research/practice; complication: infectious; infection and infectious agents; infection and infectious agents - fungal; infectious disease; lung transplantation/pulmonology; Immunology and Allergy; Transplantation; Pharmacology (medical)American Journal of Transplantation
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Transfusion-related acute lung injury after intravenous immunoglobulin treatment in a lung transplant recipient

2012

Three weeks after single-lung transplantation for pulmonary fibrosis, a patient with high serum levels of de novo donor-specific antibodies received high-dose intravenous immunoglobulin (IVIG) infusion (scheduled dose: 2 g/kg on 2 days) to prevent antibody-mediated rejection. Within the first hours after completion of infusions, he experienced acute lung injury involving the transplanted lung. Given the clinical evolution and the absence of an alternative diagnosis, transfusion-related acute lung injury (TRALI) was diagnosed. The IVIG administered on each day was from the same batch. At day 110, because of an increase in the serum titers of donor-specific antibodies, IVIG therapy was reintr…

medicine.medical_specialtybiologybusiness.industrymedicine.medical_treatmentHematologyGeneral MedicineLung injurymedicine.diseaseSurgeryTransplantationhemic and lymphatic diseasesAnesthesiaPulmonary fibrosismedicinebiology.proteinLung transplantationLung transplant recipientAntibodybusinessIVIG TherapyTransfusion-related acute lung injuryVox Sanguinis
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